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Small Things Considered
  • Ty­phus Vac­cines

    Ty­phus Vac­cines

    August 19, 2021January 30, 2026

    by Roberto — As a U.S. cit­i­zen liv­ing abroad, I of­ten get queried about COVID-19 vac­cine hes­i­tancy. Why do so many peo­ple refuse the vac­cine? Let me put it bluntly: I do not un­der­stand it.

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  • Vac­cines and the Fight Against An­tibi­otic Re­sis­tance

    Vac­cines and the Fight Against An­tibi­otic Re­sis­tance

    October 11, 2018November 19, 2025

    by Roberto — For the vast ma­jor­ity of the nat­ural his­tory of Homo sapi­ens, some 200,000 years, the av­er­age life ex­pectancy at birth has been around 30 years. What I find most amaz­ing is that as re­cently as 1900 the world av­er­age hu­man life ex­pectancy at birth had re­mained un­changed.

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  • The Louse And The Vac­cine

    The Louse And The Vac­cine

    August 24, 2015December 11, 2025

    by Elio — Sev­eral events in my life that I will re­count be­low have com­bined to make me feel con­nected to the rick­ettsiae. Con­se­quently, I was drawn to a re­cent book some­what bom­bas­ti­cally en­ti­tled "The Fan­tas­tic Lab­o­ra­tory of Dr. Weigl" by Arthur Allen.

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  • This Week in Mi­cro­bi­ol­ogy #108: Vac­cine in the time of cholera

    This Week in Mi­cro­bi­ol­ogy #108: Vac­cine in the time of cholera

    July 23, 2015February 5, 2026

    The pro­fes­sors of TWiM dis­cuss a Uni­ver­sity of Wis­con­sin plan for res­cu­ing bio­med­ical re­search in the US, and re­sults of a clin­i­cal trial in Bangladesh of an oral cholera vac­cine.

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  • Fun­gal Menin­gi­tis Bul­letin

    Fun­gal Menin­gi­tis Bul­letin

    October 25, 2012December 28, 2025

    by Elio — We sel­dom post items of im­me­di­acy, but here we in­ter­rupt our leisurely ways to write about the cur­rent dis­as­trous menin­gi­tis out­break caused by the in­jec­tion of fun­gus-con­t­a­m­i­nated steroids and other drugs. As mi­cro­bi­ol­o­gists, the ques­tion comes to mind at once: Who is the pathogen? The fun­gus im­pli­cated is Exsero­hilum rostratum(although a cou­ple…

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  • Fish­ing With Al­gae For Malaria Vac­cines

    Fish­ing With Al­gae For Malaria Vac­cines

    July 9, 2012December 29, 2025

    by James Gre­gory — Malaria is a big killer and a ma­jor world­wide health con­cern. The num­ber of malaria-re­lated deaths has fallen to ap­prox­i­mately 650,000 in 2010, from well over 1 mil­lion just ten years ago, thanks to the World Health Or­ga­ni­za­tion (WHO) and to phil­an­thropic or­ga­ni­za­tions, in­clud­ing the Bill and Melinda Gates Foun­da­tion. This ef­fort, com­posed…

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