Killing Dormant Bacteria
Noteworthy — Semapimod was identified as a killer of non-growing Gram-negative bacteria.
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Science in Stationary Phase
by Roberto — With science in stationary phase, I convey a message of hope rather than despair.
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In Praise of Small
by Roberto — At a recent breakfast chalk talk, I rekindled my love for vibrant scientific discussion, in a small setting.
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Gene Transfer Agents and Survival
by Mechas — We recently posted an update on horizontal gene transfer (HGT) to highlight the existence of strategies used by bacteria to exchange DNA – in addition to those traditionally acknowledged, that is transformation, transduction and conjugation. One of these more recently recognized mechanisms involves entities called gene transfer agents (GTAs).
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E. coli aficionados, do your strains have the wild-type rpoS gene?
by Roberto — For many of you, the rpoS allele in your E. coli strains might not matter. But if you are interested in the general stress response or adaptations to stationary phase, you might want to know if you are starting out with a wild-type rpoS gene.
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Protect Your Genes and Express Yourself
by Roberto — For any complex process to run efficiently, compartmentalization is essential. In my kitchen, results would be inedible if I did not have the information (recipes in my laptop) separate from the reactions (bowls, oven, etc.) and the cleaning (sink) and, importantly, ways to move the process of cooking from compartment to compartment.
