The TWiM team ven­tures into preprint space with an analy­sis of type VI se­cre­tion across hu­man gut mi­cro­bio­mes, and pro­vide in­sight into uri­nary tract in­fec­tion: how blad­der ex­po­sure to a mem­ber of the vagi­nal mi­cro­biota trig­gers E. coli egress from la­tent reser­voirs.