by Christoph — If there is one ven­er­a­ble la­bo­ra­to­ry tech­nique in vi­ro­lo­gy, it is the plaque as­say for the de­tect­ion and quan­ti­fi­ca­tion of bac­te­rio­pha­ges. It was pio­neer­ed by Fe­lix d'He­rel­le al­ready around 1917, and in the ear­ly 1950s, plaque as­says were also es­tab­lish­ed for eu­kar­yot­ic vi­rus­es...