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  • Black Death Mys­ter­ies

    Black Death Mys­ter­ies

    May 11, 2026May 18, 2026

    by Me­chas — A new ex­pla­na­tion for the spread of the plague-caus­ing Yersinia pestis.

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  • TWiM 285: How plague got deadly

    TWiM 285: How plague got deadly

    May 4, 2023February 5, 2026

    TWiM re­veals a new type of satel­lite virus that re­quires only phage tails for pro­duc­ing in­fec­tious virus par­ti­cles, and that highly vir­u­lent plague bac­te­ria dif­fers from its in­nocu­ous en­teric pre­de­ces­sor by its re­sis­tance to ly­sis by hu­man com­ple­ment.

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  • On the Source of the Black Death

    On the Source of the Black Death

    February 13, 2023October 21, 2025

    by Roberto — Yersinia pestis. How im­me­di­ate our re­ac­tion can be to the species name of this bac­terium, mak­ing us con­jure up im­ages of pesti­lence. As its dis­cov­erer, Alexan­der Yersin, wrote in 1894 of an out­break of bubonic plague in Hong Kong, this is the "bacille de la peste." (Work­ing in­de­pen­dently, Ki­tasato Shibasaburo also char­ac­ter­ized the plague bac­terium at nearly the ex­act same time.)

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  • Live at ASM Biode­fense 2016 — TWiM #121

    Live at ASM Biode­fense 2016 — TWiM #121

    February 17, 2016February 5, 2026

    This Week in Mi­cro­bi­ol­ogy (TWiM) host, Vin­cent Racaniello, sits down with Re­bekah Kad­ing and Wyn­d­ham Lathem at the ASM Biode­fense and Emerg­ing Dis­eases Re­search meet­ing to have a con­ver­sa­tion about their work on Rift Val­ley Fever virus and other vec­tor-borne pathogens, and the evo­lu­tion and patho­gen­e­sis of Yersinia pestis, the agent of plague.

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  • TWiM #80: Hurl­ing Fleas and De­signer Chro­mo­somes

    TWiM #80: Hurl­ing Fleas and De­signer Chro­mo­somes

    June 13, 2014February 5, 2026

    Vin­cent, Elio, and Michele dis­cuss how to syn­the­size a de­signer yeast chro­mo­some, and de­ci­pher­ing the ge­netic changes path that al­lowed Yersinia pestis to be trans­mit­ted by fleas.

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  • A Pestis from the Past

    A Pestis from the Past

    November 7, 2011January 1, 2026

    by S. Mar­vin Fried­man — In re­cent decades we've come to re­al­ize that vic­tory goes not to the swift or to the strong, but to the im­mune. The in­tro­duc­tion of agents of deadly dis­eases into im­muno­log­i­cally naïve pop­u­la­tions de­ter­mined mo­men­tous events in hu­man his­tory. The con­quest of the Amer­i­cas re­sulted in good part from the…

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