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Small Things Considered
  • Weak­en­ing The My­colic Acid Fortress of M. tu­ber­cu­lo­sis

    Weak­en­ing The My­colic Acid Fortress of M. tu­ber­cu­lo­sis

    April 11, 2016December 9, 2025

    by Monika Buczek — Tu­ber­cu­lo­sis (TB), is an in­fec­tious dis­ease caused by the bac­terium My­cobac­terium tu­ber­cu­lo­sis (Mtb). Symp­toms of an ac­tive TB in­fec­tion in­clude chronic cough with blood-tinged spu­tum, fever, and weight loss. In fact, prior to the 1882 dis­cov­ery of the mi­crobe by Robert Koch, TB was called "con­sump­tion" be­cause the rapid rate with which in­fected pa­tients lost body mass made them ap­pear to be "con­sumed" by some un­known en­tity.

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  • Koch's De­vel­op­ment of Early In­sta­Gram Pos­i­tive Pho­tog­ra­phy

    Koch's De­vel­op­ment of Early In­sta­Gram Pos­i­tive Pho­tog­ra­phy

    May 16, 2013December 23, 2025

    Pic­tures Con­sid­ered #4 by Daniel P. Haeusser — Robert Koch is one of the key fig­ures in early bac­te­ri­ol­ogy, help­ing de­velop cul­ture tech­niques (e.g. solid me­dia), crit­i­cal rea­son­ing (e.g. Koch's pos­tu­lates), and dis­ease eti­ol­ogy (e.g.cholera and tu­ber­cu­lo­sis). He also pub­lished the first pho­tomi­cro­graphs of bac­te­ria (Fig­ure 1A) in his 1877 pa­per­Ver­fahren zur Un­ter­suchung, zum Con­servieren und Pho­tographiren…

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  • My­cobac­te­ria Make Spores?

    My­cobac­te­ria Make Spores?

    July 16, 2009January 8, 2026

    by Pe­ter Set­low — Rarely does news come along that threat­ens to over­turn our cher­ished be­liefs. Since early af­ter the dis­cov­ery of tu­ber­cle bacilli by Robert Koch in 1882, the my­cobac­te­ria have been con­sid­ered not to be spore for­m­ers. Now this is be­ing chal­lenged by a new re­port.

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  • The Proper Study of Man Is Bac­te­ria

    The Proper Study of Man Is Bac­te­ria

    March 25, 2007January 21, 2026

    by Elio — It is of more than pass­ing in­ter­est to know which in­fec­tious dis­eases did be­set an­cient hu­mans. Such in­for­ma­tion may il­lu­mi­nate be­hav­ioral and cul­tural pat­terns dif­fi­cult to ob­tain from other sources. Thanks to mod­ern tech­nol­ogy, it is pos­si­ble to iden­tify mi­cro­bial DNAs found in an­cient hu­man re­mains. One of the most...

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