Vin­cent and Michael travel to San Fran­cisco for the 52nd In­ter­science Con­fer­ence on An­timi­cro­bial Agents and Chemother­apy (ICAAC), where they meet with Bill, John, and Vic­tor to dis­cuss tu­ber­cu­lo­sis, mon­i­tor­ing in­fec­tious dis­ease out­breaks with on­line data, and out­side-the-box ap­proaches to an­tibac­te­r­ial ther­apy.