• Grant's Anatomy

    by Christoph — At an EMBO work­shop in Copen­ha­gen in 2006 on 'Cell cy­cle and cy­to­ske­le­tal ele­ments in bac­te­ria,' I was al­most un­able to stay put in my seat dur­ing one pre­sen­ta­tion: Grant Jen­sen showed the 3D-mon­­tage of cry­oET ima­ges of mag­ne­to­somes in Mag­ne­to­spi­ril­lum mag­ne­to­tac­ti­cum. It was a vi­su­al jour­ney in­to and through the in­ter­ior of a cell,...

  • Con­ju­ga­tion, and some pair­ing is­sues

    Pic­tures Con­sid­ered #55 by Christoph — If you've ever taken a class on bac­te­ri­al ge­ne­tics, ei­ther re­cent­ly or in the last few de­ca­des, you've no doubt seen this im­age: the con­ju­ga­tion of two bac­te­ri­al cells (Fig­ure 1). And if you found this im­age so self-ex­­pla­­na­­to­ry that you didn't both­er to ask for the source, you're not alone. The in­ter­net is re­plete with it, in vary­ing...

  • Get­ting to grips with the in­tan­gi­ble

    by Christoph — Imag­ine the E. coli nu­cleoid as a swig but of of a high­ly vis­cous tan­gle of a 2 nm thin and ~1.5 mm long DNA poly­mer, de­co­rat­ed with and high­ly com­pact­ed by a ple­tho­ra of pro­teins, and some­how sus­pend­ed in the cy­to­plasm of a cell with a vol­ume of ~1.3 µm³. It's vir­tu­al­ly im­pos­si­ble to "grip" the nu­cleoid, to mea­sure...

  • Strep­to­myces spores tak­ing a ride...

    by Christoph — Strep­to­mycetes, these non-motile Acti­nobac­te­ria that are ca­pa­ble of mycelial growth much like fungi, are quite in­ven­tive when it comes to the dis­tri­b­u­tion of their spores. They don't just rely on en­chant­ing scents like geosmin that they emit to at­tract spring­tails, which trans­port their spores over long dis­tances (see Roberto's re­cent post). They also rou­tinely em­ploy bac­te­r­ial trans­port work­ers.

  • Space-tol­er­ant Mi­cro­nauts

    by Alise Muok and Ar­i­ane Briegel — Try to imag­ine a crea­ture that can sur­vive from the heat of 150°C (300°F) to the cold of –270°C (–454°F), in the ab­sence of oxy­gen, af­ter com­plete de­hy­dra­tion, at 1,000× at­mos­pheric pres­sure, and af­ter the ra­di­a­tion and vac­uum of space. Who might such space trav­el­ers be?

  • Where Art Thou, O Ri­bo­some?

    by Elio — In a re­cent post (The Age of Imag­ing), I mused about ad­vances in mi­croscopy that are rev­o­lu­tion­iz­ing our con­cept of bac­te­r­ial cell struc­ture. High on the list of amaz­ing de­vel­op­ments is cry­o­elec­tron to­mog­ra­phy (CET), a tech­nique that al­lows one to look in­side bac­te­r­ial cells. Flash-freez­ing cells at very low tem­per­a­tures...