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Small Things Considered
  • TWiM #66: The Shape of a Con­tainer

    TWiM #66: The Shape of a Con­tainer

    October 18, 2013February 5, 2026

    Vin­cent, Elio, Michael, and Michele dis­cuss the cu­ri­ous outer mem­brane vesi­cles of Neis­se­ria menin­gi­tides, and sources of Clostrid­ium dif­fi­cile in­fec­tion re­vealed by genome se­quenc­ing.

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  • The Bile Salt Giveth and the Bile Salt Taketh Away

    The Bile Salt Giveth and the Bile Salt Taketh Away

    April 3, 2008January 9, 2026

    by Elio — We needn't be re­minded that path­o­genic mi­cro­bi­ol­ogy is a branch of mi­cro­bial ecol­ogy but a nice ex­am­ple helps makes the point. The story is about a nasty dis­ease, pseudomem­bra­nous col­i­tis, which af­fects mainly im­muno-com­pro­mised peo­ple who have been on an­tibi­otics and are ly­ing in a hos­pi­tal bed. The dis­ease, as the name sug­gests, is an...

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