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  • TWiM #102: Hap­pi­ness is the spore-for­m­ers in your gut

    TWiM #102: Hap­pi­ness is the spore-for­m­ers in your gut

    April 29, 2015February 5, 2026

    The TWiM team dis­cusses ev­i­dence that sero­tonin syn­the­sis is reg­u­lated by spore-form­ing mem­bers of the gut mi­cro­biota.

    Read More TWiM #102: Hap­pi­ness is the spore-for­m­ers in your gutContinue

  • When An­tibi­otic Re­sis­tance in vitro Does Not Tell You...

    When An­tibi­otic Re­sis­tance in vitro Does Not Tell You...

    March 23, 2015December 13, 2025

    ...What You Need To Know by Terry Roe­mer — In­creas­ingly, it is be­com­ing ap­par­ent that there is a deep dif­fer­ence be­tween what hap­pens in vivo and in vitro. The idea that one can com­fort­ably ex­trap­o­late from the bench to, say, the bed­side, is re­ced­ing rapidly. Liv­ing things, not even the small­est ones, are no agar plates, how­ever con­ve­nient and in­ex­pen­sive these may be.

    Read More When An­tibi­otic Re­sis­tance in vitro Does Not Tell You...Continue

  • Flights of Dis­cov­ery

    Flights of Dis­cov­ery

    May 19, 2014December 18, 2025

    by Mizuho Ota — I won­der if you are fa­mil­iar with this icon. It de­picts the "eye­drop­per," a com­monly used tool in com­puter graph­ics and paint­ing pro­grams that al­lows you to choose any spot on an im­age and iden­tify its ex­act color. On a com­puter this is easy in­for­ma­tion to ob­tain; how­ever, in deal­ing with real ma­te­ri­als, the ques­tion "but what ex­actly IS it?"…

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  • TWiM #76: Ge­netic Biopix­els and a Path­o­genic Sweet Tooth

    TWiM #76: Ge­netic Biopix­els and a Path­o­genic Sweet Tooth

    April 15, 2014February 5, 2026

    Vin­cent, Elio, Michael, and Michele dis­cuss the use of bac­te­ria to build a ge­netic sen­sor for heavy met­als, and how host sug­ars help en­teric pathogens to ex­pand af­ter an­tibi­otic treat­ment.

    Read More TWiM #76: Ge­netic Biopix­els and a Path­o­genic Sweet ToothContinue

  • No Bac­terium Is An Is­land

    No Bac­terium Is An Is­land

    May 6, 2013December 23, 2025

    by S. Mar­vin Fried­man — To para­phrase an old adage, no bac­terium is an is­land. In­deed, bac­te­ria in na­ture ex­ist as polymi­cro­bial com­mu­ni­ties where in­ter­ac­tions be­tween in­di­vid­u­als in­flu­ence ac­tiv­i­ties of the en­tire pop­u­la­tion. This is es­pe­cially true of path­o­genic bac­te­ria, al­though it has been mostly ig­nored be­cause we fre­quently iso­late a sin­gle species from an in­fec­tion…

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  • TWiM #51: Cave Sci­ence with Hazel Bar­ton

    TWiM #51: Cave Sci­ence with Hazel Bar­ton

    February 28, 2013February 5, 2026

    Vin­cent, Michael, and Elio meet up with Hazel Bar­ton to talk about cave mi­cro­bi­ol­ogy.

    Read More TWiM #51: Cave Sci­ence with Hazel Bar­tonContinue

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