TWiM 289: Vi­ral De­fense and Counter-De­fense

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TWiM high­lights vi­ral de­fense and counter-de­fense: cGAS me­di­ated ubiq­ui­ti­na­tion to counter in­fec­tion, and vi­ral sponges that se­quester nu­cleotide sig­nals to in­ac­ti­vate im­mu­nity.

Hosts: Vin­cent Racaniello, Michael Schmidt, Michele Swan­son, Pe­tra Levin.
 

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Links for this episode

• Ubiq­ui­tin-like con­ju­ga­tion by bac­te­r­ial cGAS (Na­ture)
• Jumpin' Jack Flash (TWiV 222)
• Vi­ral sponges in­ac­ti­vate anti-phage im­mu­nity (Trends Mi­cro)
• cGAS and CD-NTase en­zymes (Curr Opin Struct Biol)
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