Ret­ro­spec­tive, De­cem­ber 2008

We present here a lightly an­no­tated list that in­cludes most of our posts from the past half year.

The Teach­ers' Cor­ner

We re­cently added a new sec­tion to our blog, where the posts are or­ga­nized in a more teacher-friendly for­mat. We hope that this will in­crease the use of these ar­ti­cles in the class­room.

The View From Here

Sev­eral dis­tin­guished mi­cro­bi­ol­o­gists have shared with us their thoughts and per­spec­tives.

The Search for Achilles' Heel  John Cof­fin pro­poses some darn good rea­sons why an ef­fec­tive HIV vac­cine is hard to come by.

Back to the Wild!  Tried and true lab­o­ra­tory strains are great to work with, right? Richard Losick ex­plains why this fo­cus may be in­suf­fi­cient, and even mis­lead­ing.

The "Par­vome"  Ju­lian Davies pon­ders (in his inim­itable way) the mean­ing of all those small mol­e­cules that mi­crobes make.

Tal­mu­dic Ques­tions

#36, #37, #38, #39,#40, #41, #42

Of Terms in Bi­ol­ogy

Of Terms in Bi­ol­ogy: Syn­teny  by Elio

Fine Read­ings

A well-writ­ten re­view ar­ti­cle makes for par­tic­u­larly re­ward­ing read­ing. We picked a few that we think fit this bill.

The Hy­brid Two-En­gine Sys­tem of Myxobac­te­ria  Myxobac­te­ria move on sur­faces by pulling them­selves for­ward and push­ing from be­hind. When they re­verse di­rec­tion, the two poles swap roles. (pub­lished in 2009)

The Ori­gins of Mul­ti­cel­lu­lar­ity  How did we get to where we are? At least, how did we get started?

E. coli Goes Green  Tom Bern­hardt salutes Ted Park for a life­time of work on pep­ti­do­gly­can.

A Quick Guide to the Bac­te­r­ial Fla­gel­lar Mo­tor  Is there any­thing more ex­cit­ing that the bac­te­r­ial fla­gel­lar ap­pa­ra­tus? We dare you!

Metage­nomics  Noth­ing like be­ing lazy on a nice Au­tumn week­end. If you are so in­clined, and yet you are won­der­ing about metage­nomics and specif­i­cally about what it has done for our un­der­stand­ing of the mi­cro­bial world, here's a sat­is­fy­ing piece by Hugen­holtz and Tyson. For those who can't wait to read it, here are some...

Eu­kary­otic Mi­crobes

Gi­a­r­dia "I Did It My Way"  Much like other pathogens, Gi­a­r­dia change their anti­genic coat to evade the im­mune re­sponse. But they do it their way, by us­ing RNA in­ter­fer­ence to sup­press ex­pres­sion of the un­wanted anti­gens. (pub­lished in 2009)

The Fastest Flights in Na­ture  Nick Money knows how to stop ul­tra-fast phe­nom­ena in their tracks. He has a cam­era that takes hun­dreds of thou­sands of frames per sec­ond. See here the amaz­ing flight of Pi­lobo­lus spores.

Pico Who?  Lit­tle did we know un­til re­cently that tiny al­gae (the Pi­coplank­ton) make up a huge amount of the bio­mass in the oceans.

The Mush­room Week

Why shouldn't mush­rooms have a week of their own? A mush­room a day… Here is what we posted:

Let Them Eat Mush­rooms
The Mush in Mush­rooms
Deadly Pret­zels
Fid­dling with Fungi
But Is It Good to Eat?

Patho­gen­e­sis

Pre­vent­ing In­fec­tions by Dis­pelling Sphig­no­rance  Norm Radin sheds needed light on sphin­golipids, pre­mier mul­ti­func­tional bi­o­log­i­cal chem­i­cals. (pub­lished in 2009)

The Two Edges of the An­tibi­otic Sword  An­tibi­otics are al­ways good for you, right? Joshua Fierer dis­cusses yet an­other rea­son for cau­tion.

Sex­u­ally Avoided Dis­ease  When it comes to vi­ral in­fec­tions, does be­ing hap­loid or diploid make a dif­fer­ence to mi­croal­gae? You bet­ter be­lieve it does. Willie Wil­son ex­plains why.

Evo­lu­tion, Ecol­ogy, and Other Good Stuff

A Glimpse Into the World of Metage­nomics  No tech­nique stands alone, and Don­ald Klein paints a cau­tion­ary pic­ture why this is true for metage­nomics. (pub­lished in 2009)

Jump­ing Genes, Wol­bachia Style  Surely prokary­otes and eu­kary­otes have been swap­ping genes for eons. Ev­i­dence, ev­i­dence… ? Well, here's at least one case.

Source

De Pro­fundis…  Know any place on Earth where there is a pure cul­ture of one Bac­te­ria? (In the lab or an in­fected host doesn't count.) Look deep enough and you will find one.

In­trater­res­tri­als  Manuel Sánchez dis­cusses the Bac­te­ria in rocks and what they might be do­ing there.

Big Game Hunt­ing, Bac­te­r­ial Style  Bac­te­ria hunt for al­gae in the oceans, and they can take down even the motile di­nofla­gel­lates of­ten as­so­ci­ated with red tides.

You Can't Judge a Book by Its Cover  What are GTAs? Yet one more way that bac­te­r­ial genes travel from cell to cell.

Species Come and Species Go  Campy­lobac­ter seems to spe­ci­ate and de-spe­ci­ate with gusto.

Sym­bio­sis

Wol­bachia In­fec­tion: A Good Thing?  This most fa­mous of insect/bacteria sym­bioses turns out to be ben­e­fi­cial to the host in un­ex­pected ways. (pub­lished in Jan­u­ary 2009)

The More the Mer­rier  How many dif­fer­ent types of or­gan­isms par­tic­i­pate in the sym­bio­sis be­tween the leaf-cut­ting ant and its fun­gus? The num­ber keeps in­creas­ing.

How Many Genomes Does It Take to Change a Light Bulb?  Well, what we meant is: how many genomes does it take to make tryp­to­phan in aphids? At least one more than you might have thought.

What Are Lit­tle Bugs Made Of?

The Se­crets of the Sac­cu­lus  A mas­ter of the "pep­ti­do­gly­can art" (and sci­ence), Hans Mar­tin, ex­plores some of what we know and what we still don't know about this most bac­te­r­ial of mol­e­cules.

The User's Guide to Poly-γ-Glu­ta­mates  Who are the users of these cos­mopoli­tan mol­e­cules? As di­verse as bac­te­r­ial cap­sules and the ne­ma­to­cyst-fir­ing mech­a­nisms of jel­ly­fish.

Where Art Thou, O Nu­cleoid?  Con­rad Woldringh poses some chal­lenges to cher­ished no­tions about the physics of bac­te­r­ial nu­cleoids.

What Else is Go­ing On?

News from the De­part­ment of Mimivi­rol­ogy: Part II  Vi­rophage is a newly minted term for satel­lite viruses. But there is more to it than just ter­mi­nol­ogy be­cause it in­volves those vi­ral out­liers, the Mimiviruses.

Some More Per­sonal Com­ments

Of Fly Pa­per, Es­peranto, Al­gae, Po­ems, and Po­lar Bears: In Mem­ory of Ralph Lewin Ralph Lewin was unique among mi­cro­bi­ol­o­gists and among hu­man be­ings. Here we of­fer some ev­i­dence to con­vince you. (Click here for an amus­ing tale.)

Mus­ings: The Guild  Be­ing a mi­cro­bi­ol­o­gist means more than go­ing for bi­ol­ogy in a small way.

Equa­to­r­ial Epi­demi­ol­ogy  Elio at­tended the Latin Amer­i­can Mi­cro­bi­ol­ogy Con­gress, and there heard about zinc and H. py­lori.

Fine Read­ing and Fine Mem­o­ries  An ap­pre­ci­a­tion of the late Terry Bev­eridge.

 

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